Sectie's

Groep van Ijzendoorn

Our ambition is to understand the molecular mechanisms that control the intracellular dynamics of proteins, lipids and membranes in the context of the functional organization of cells, and to understand how these mechanisms contribute to health or, when disrupted, to human disease.

In this context our focus is also on rare congenital disorders caused by disrupted intracellular protein dynamics and cellular organization, which includes elucidating their pathogenesis, development of patient-specific iPSC-based cell models and lead identification for novel therapeutic strategies.

  • People
  • Alumni
  • Dissertations
  • Students
  • Sven van IJzendoorn Prof. dr. Visit
    Position

    Professor, Projectleider

    Research fields

    Celbiologie, intracellulair eiwittransport, cellulaire organisatie

    Ondersteuning
    Promovendus
    Jeffrey Boertien (Cell Biol. /Neurol.)
  • Postdocs:
    Lucja Jarosz, 2012-2014
    Sukhdeep Galsinh, 2013
    Nai-Hua Hsiao, 2009-2011
    Matsushita Masafumi Matsushita, 2010
    Chris Mee, 2010
    Ryuichi Ohgaki, 2009
    Kati Juuti-Uusitalo, 2009-2010
    Chris Mee, 2008
    Kousei Ito, 2008
    Tounsia Ait-Slimane, 2004
    Tetsuo Nakayima, 2004

    PhD students:
    Leon Klunder, 2012-2016
    Herschel Dhekne, 2010-2014
    Christiaan Slim, 2010-2014
    Magdalena Golachowska, 2007-2011
    Kacper Wojtal, 2003-2007
    Delphine Théard, 2002-2006
    Joke van der Wouden, 2000-2004

  • Dissertations supervised by Sven C.D. van IJzendoorn (co-) promotor or assessor):

    2019

    van de Peppel, I. P. (2019). Intestinal bile acid reabsorption in health and disease. [Groningen]: Rijksuniversiteit Groningen.

    Cong, Y-Y. (2019). Molecular insights into viral respiratory infections. [Groningen]: University of Groningen.

    Wijers, M. (2019). Sorting out cholesterol metabolism: novel insights into the mechanism of endosomal trafficking of lipoprotein receptors. [Groningen]: Rijksuniversiteit Groningen. https://doi.org/10.33612/diss.102035320

    2018

    Rodrigues de Abreu, S. (2018). New insights into autophagy regulation using yeast Saccharomyces cerevisiae. [Groningen]: University of Groningen.

    Pinto, F. (2018). Unraveling VPS13A pathways: from Drosophila to human.  [Groningen]: University of Groningen.

    2017

    Kirschbaum, M. (2017). Molecular mechanisms of platelet-mediated liver regeneration after partial hepatectomy [Groningen]: Rijksuniversiteit Groningen

    2016

    Hoornweg, T. E. (2016). Breaking barriers: Early events in chikungunya and dengue virus infections [Groningen]: Rijksuniversiteit Groningen

    Poppinga, W. J. (2016). Compartmentalized signaling in the lung: A-kinase anchoring proteins as novel drug targets for chronic obstructive pulmonary disease[Groningen]: University of Groningen

    Klunder, L. J. (2016). Effects of lifestyle and environmental factors on intestinal epithelial cell morphogenesis [Groningen]: Rijksuniversiteit Groningen

    Fedoseienko, A. (2016). Identification of a novel multiprotein complex in cargo sorting that preserves metabolic pathways in the liver [Groningen]: University of Groningen

    2014

    Dhekne, H. S. (2014). Pathogenic mechanisms in microvillus inclusion diseaseGroningen: s.n.

    Slim, C. (2014). The polarized architecture of hepatocytes: Regulation by intrinsic and extrinsic factors [S.l.]: [S.n.]

    2011

    Golachowska, M. R. (2011). Microvillus Inclusion Disease. Lessons about the apical plasma membrane. Groningen: s.n.

    1999

    IJzendoorn, S. C. D. V. (1999). Transport and sorting of sphingolipids in polarized cells: the involvement of the sub-apical compartment s.n.

  • Student projects:

    Students interested in an internship in our group are welcome to discuss possibilities.

    You can apply via this application form.

Share this:
Your browser is out-of-date!

Update your browser to view this website correctly. Update my browser now

×