- - English
Our ambition is to understand the molecular mechanisms that control the intracellular dynamics of proteins, lipids and membranes in the context of the functional organization of cells, and to understand how these mechanisms contribute to health or, when disrupted, to human disease.
In this context our focus is also on rare congenital disorders caused by disrupted intracellular protein dynamics and cellular organization, which includes elucidating their pathogenesis, development of patient-specific iPSC-based cell models and lead identification for novel therapeutic strategies.
Professor, Projectleider
Celbiologie, intracellulair eiwittransport, cellulaire organisatie
Postdocs:
Lucja Jarosz, 2012-2014
Sukhdeep Galsinh, 2013
Nai-Hua Hsiao, 2009-2011
Matsushita Masafumi Matsushita, 2010
Chris Mee, 2010
Ryuichi Ohgaki, 2009
Kati Juuti-Uusitalo, 2009-2010
Chris Mee, 2008
Kousei Ito, 2008
Tounsia Ait-Slimane, 2004
Tetsuo Nakayima, 2004
PhD students:
Leon Klunder, 2012-2016
Herschel Dhekne, 2010-2014
Christiaan Slim, 2010-2014
Magdalena Golachowska, 2007-2011
Kacper Wojtal, 2003-2007
Delphine Théard, 2002-2006
Joke van der Wouden, 2000-2004
2023
van Schaik, P., 2023, [Groningen]: University of Groningen. 275 p.
Sun, Y., 2023, [Groningen]: University of Groningen. 142 p.
Li, Q., 2023, [Groningen]: University of Groningen. 169 p.
Boertien, J., 2023, [Groningen]: University of Groningen. 177 p.
2020
de Jong, E., 2020, [Groningen]: University of Groningen. 116 p.
Overeem, A. W., 2020, [Groningen]: Rijksuniversiteit Groningen. 225 p.
The roles of MYO5B in epithelial cells and the intestine: A focus on microvillus inclusion disease
Leng, C., 2020, [Groningen]: University of Groningen. 224 p.
2019
van de Peppel, I. P. (2019). Intestinal bile acid reabsorption in health and disease. [Groningen]: Rijksuniversiteit Groningen.
Cong, Y-Y. (2019). Molecular insights into viral respiratory infections. [Groningen]: University of Groningen.
Wijers, M. (2019). Sorting out cholesterol metabolism: novel insights into the mechanism of endosomal trafficking of lipoprotein receptors. [Groningen]: Rijksuniversiteit Groningen. https://doi.org/10.33612/diss.102035320
2018
Unraveling VPS13A pathways: from Drosophila to human
Pinto, F., 2018, [Groningen]: University of Groningen. 153 p.
Rodrigues de Abreu, S. (2018). New insights into autophagy regulation using yeast Saccharomyces cerevisiae. [Groningen]: University of Groningen.
2017
Kirschbaum, M. (2017). Molecular mechanisms of platelet-mediated liver regeneration after partial hepatectomy [Groningen]: Rijksuniversiteit Groningen
2016
Effects of lifestyle and environmental factors on intestinal epithelial cell morphogenesis
Klunder, L. J., 2016, [Groningen]: Rijksuniversiteit Groningen. 204 p.
Hoornweg, T. E. (2016). Breaking barriers: Early events in chikungunya and dengue virus infections [Groningen]: Rijksuniversiteit Groningen
Poppinga, W. J. (2016). Compartmentalized signaling in the lung: A-kinase anchoring proteins as novel drug targets for chronic obstructive pulmonary disease[Groningen]: University of Groningen
Fedoseienko, A. (2016). Identification of a novel multiprotein complex in cargo sorting that preserves metabolic pathways in the liver [Groningen]: University of Groningen
2014
Pathogenic mechanisms in microvillus inclusion disease
Dhekne, H. S., 2014, Groningen: s.n.. 144 p.
The polarized architecture of hepatocytes: Regulation by intrinsic and extrinsic factors
Slim, C., 2014, [S.l.]: [S.n.]. 153 p.
2011
Microvillus Inclusion Disease. Lessons about the apical plasma membrane.
Golachowska, M. R., 2011, Groningen: s.n.. 214 p.
1999
IJzendoorn, S. C. D. V. (1999). Transport and sorting of sphingolipids in polarized cells: the involvement of the sub-apical compartment
Student projects:
Students interested in an internship in our group are welcome to discuss possibilities.
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