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This animated movie presents the mechanism of macroautophagy, hereafter autophagy, by showing the molecular features of the formation of autophagosomes, the hallmark organelle of this intracellular catabolic pathway. It is based on our current knowledge and it also illustrates how autophagosomes

Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex. Gerrits E, Giannini LAA, Brouwer N, Melhem S, Seilhean D, Le Ber I; Brainbank Neuro-CEB Neuropathology Network, Kamermans A, Kooij G, de Vries HE, B

Epigenetic regulation of innate immune memory in microglia. Zhang X, Kracht L, Lerario AM, Dubbelaar ML, Brouwer N, Wesseling EM, Boddeke EWGM, Eggen BJL, Kooistra SM. J Neuroinflammation. 2022 May 14;19(1):111.  

Radiation-induced cardiac side-effects: The lung as target for interacting damage and intervention Julia Wiedemann, Robert P. Coppes and Peter van Luijk Front. Oncol., 22 July 2022

2022 BBRF Young Investigator Grants for Inge Holtman and Marieke Begemann. The Brain & Behavior Research Foundation (BBRF) awards the Young Investigator Grant to promising investigators to launch their careers in neuroscience and psychiatry as independent research faculty, and gather pilot

Fifteen highly promising researchers, who recently received their PhDs, received a Rubicon grant from NWO this week. This grant provides them with the opportunity to gain international research experience and allows them to realise their own research plans at renowned foreign researchÂ

Neuroscientist Marie-José van Tol is awarded a Vidi grant worth 800.000 euros by the Dutch Research Council. The grant enables her to develop her own innovative line of research and set up their own research group in the coming five years. More information about het reseach program

CD146 increases stemness and aggressiveness in glioblastomaand activates YAP signaling Yuanke Liang,  Daniëlle Voshart, Judith T. M. L. Paridaen, Nynke Oosterhof,  Dong Liang, Arun Thiruvalluvan, Inge S. Zuhorn, Wilfred F. A. den Dunnen, Guojun Zhang,  Haoyu Lin, Lara Barazzuol, Frank A. E.

The jury has nominated six scientific research projects from 31 entries for the Huibregtsen Prize 2022. A project of Iris Sommer is one of the nominated projects. On the Evening of Science & Society, October 10, 2022 in the Pieterskerk in Leiden, jury chair Marileen Dogterom (KNAW president)

Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae Noura Faraj, B. H. Peter Duinkerken, Elizabeth C. Carroll, Ben N. G. Giepmans FEBS Letters. 29 May 2022 https://doi.org/10.1002/1873-3468.14411