News

Role of mTOR through Autophagy in Esophageal Cancer Stemness by Liang Du, Da Wang, Peter W. Nagle, Andries A. H. Groen, Hao Zhang, Christina T. Muijs, John Th. M. Plukker and Robert P. Coppes Cancers 2022, 14(7), 1806; https://doi.org/10.3390/cancers14071806

Tyrosine Phosphatase PTPRO Deficiency in ERBB2-Positive Breast Cancer Contributes to Poor Prognosis and Lapatinib Resistance Hongmei Dong, Liang Du, Song wang Cai, Wan Lin, Chaoying Chen, Matthew Still, Zhimeng Yao, Robert P. Coppes, Yunlong Pan, Dianzheng Zhang, Shegan Gao and Hao Zhang Front.

Fatigue following mild traumatic brain injury relates to visual processing and effort perception in the context of motor performance. Prak RF, Marsman JC, Renken R, van der Naalt J, Zijdewind I (2021).   Neuroimage Clin. 13; 32:102783. doi: 10.1016/j.nicl.2021.102783.

Increased Ipsilateral M1 Activation after Incomplete Spinal Cord Injury Facilitates Motor Performance. Prak RF, Marsman JC, Renken R, Tepper M, Thomas CK, Zijdewind I (2021). J Neurotrauma 38: 2988-2998. doi: 10.1089/neu.2021.0140.  

CureQ: Voorspellen, vertragen en genezen van hersenziekten veroorzaakt door  polyglutamine(Q)  Er zijn ruim tien erfelijke hersenziektes die allen veroorzaakt worden door eenzelfde type DNA-fout, waaronder de ziekte van Huntington. Recent zijn de eerste hoopgevende trials gestart, maar er z

Neural basis of positive and negative emotion regulation in remitted depression Rozemarijn S. van Kleef, Jan-Bernard C. Marsman, Evelien van Valen, Claudi L.H.Bockting, André Aleman, Marie-José van Tol NeuroImage: Clinical, Volume 34, 2022, 102988

Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome Wouter Huiting, Suzanne L Dekker, Joris CJ van der Lienden, Rafaella Mergener, Maiara K Musskopf, Gabriel V Furtado, Emma Gerrits, David Coit, Mehrno

ER-phagy: mechanisms, regulation and diseases connected to the lysosomal clearance of the endoplasmic reticulum Fulvio Reggiori, Maurizio Molinari Physiol Rev 2022 Feb 21.  doi: 10.1152/physrev.00038.2021. Online ahead of print.

ER-phagy requires the assembly of actin at sites of contact between the cortical ER and endocytic pits Liu D, Mari M, Li X, Reggiori F, Ferro-Novick S, Novick P. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2117554119. doi: 10.1073/pnas.2117554119. PMID: 35101986