News

Getting on the right track: Interactions between viruses and the cytoskeletal motor proteins Rio Berge C, Cong Y, Reggiori F Traffic, in press.  

Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology Misrielal C, Alsema AM, Wijering MHC, Miedema A, Mauthe M, Reggiori F, Eggen BJL Brain Behav Immun Health, in press.

Digest it all: The lysosomal turnover of cytoplasmic aggregates Mauthe M, Kampinga HH, Hipp MS, Reggiori F Trends Biochem Sci, in press.

ER-phagy requires the assembly of actin at the contact sites between the cortical ER and endocytic pits Liu D, Mari M, Li X, Reggiori F, Ferro-Novick S, Novick P Proc Natl Acad Sci USA, 119, e2117554119.

mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation SCYL1 Kaeser-Pebernard S, Vionnet C, Mari M, Siva Sankar D, Hu Z, Roubaty C, Martinez E, Zhou H, Spuck-Calvar M, Petri-Fink A, Rainer G, Steinberg F, Reggiori F, Dengjel J Nat Comm, 13, 4685. 

The lipid flippase Drs2 regulates anterograde transport of Atg9 during autophagy (2022) Kriegenburg F, Huiting W, van Buuren-Broek F, Zwilling E, Hardenberg R, Mari M, Kraft C, Reggiori F Autophagy Rep, 1, 345–367.

The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis. F. Elsiena Kuiper, Paola Gallardo, Tessa Bergsma, Muriel Mari, Maiara Kolbe Musskopf, Jeroen Kuipers, Ben N. G. Giepmans, Anton Steen, Harm H. Kampinga, Liesbeth M. Veenhoff, Steven Berg

Role of quiescent cells in the homeostatic maintenance of the adult submandibular salivary gland Paola Serrano Martinez, Martti Maimets, Reinier Bron, Ronald van Os, Gerald de Haan, Sarah Pringle, Robert P. Coppes iScience, VOLUME 25, ISSUE 10, 105047, OCTOBER 21, 2022

Iris Sommer krijgt Huibregtsenprijs voor ‘ongelijke medische behandeling van vrouwen en mannen’. Op de drieëntwintigste Avond van Wetenschap & Maatschappij, gisteravond in de Pieterskerk in Den Haag, heeft prof. dr. I. Sommer de Huibregtsenprijs 2022 gekregen voor haar onderzoeksproject

This animated movie presents the mechanism of macroautophagy, hereafter autophagy, by showing the molecular features of the formation of autophagosomes, the hallmark organelle of this intracellular catabolic pathway. It is based on our current knowledge and it also illustrates how autophagosomes