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Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state. Voshart DC, Oshima T, Jiang Y, van der Linden GP, Ainslie AP, Reali Nazario L, van Buuren-Broek F, Scholma AC, van Weering HRJ, Brouwer N, Sewdihal J, Brouwer U, Coppes RP, Holtman IR, Eggen BJL, Koois

Het MS Centrum Noord Nederland (MSCNN) ontvangt 800.000 euro om het onderzoek naar de ziekte multiple sclerose voort te zetten. Speerpunt in het MSCNN-onderzoek is het onderzoek naar myeline in de breedst mogelijk zin. Myeline, de isolatielaag rondom de zenuwvezels, raakt beschadigd bij mensen met M

Nanoparticles targeting the intestinal Fc receptor enhance intestinal cellular trafficking of semaglutide. Pinto S, Hosseini M, Buckley S, Yin W, Garousi J, Gräslund T, van Ijzendoorn S, Santos HA, Sarmento B. J. Contr. Rel., Volume 366, February 2024, Pages 621-636. doi: 10.1016/j.jconrel.2024

Optical STEM detection for scanning electron microscopy Arent J. Kievits, B.H. Peter Duinkerken, Job Fermie, Ryan Lane, Ben N.G. Giepmans, Jacob P. Hoogenboom Volume 256, February, 113877. DOI 10.1016/j.ultramic.2023.113877  

Glioblastoma and its treatment are associated with extensive accelerated brain aging. Anna P. Ainslie, Myrthe Klaver, Daniëlle C. Voshart, Emma Gerrits, Wilfred F. A. den Dunnen, Bart J. L. Eggen, Steven Bergink, Lara Barazzuol. Aging Cell 2024 17 January https://doi.org/10.1111/acel.14066. Pd

Mitophagy induction improves salivary gland stem/progenitor cell function by reducing senescence after irradiation. Cinat D, Lena De Souza A, Soto-Gamez A, Jellema-de Bruin AL, Coppes RP, Barazzuol L. Radiother Oncol. 2023 Nov 23:110028. doi: 10.1016/j.radonc.2023.110028. Online ahead of print.

Mesenchymal stem cell-derived HGF attenuates radiation-induced senescence in salivary glands via compensatory proliferation. Soto-Gamez A, van Es M, Hageman E, Serna-Salas SA, Moshage H, Demaria M, Pringle S, Coppes RP. Radiother Oncol. 2023 Nov 4;190:109984. doi: 10.1016/j.radonc.2023.109984.

MET-receptor targeted fluorescent imaging and spectroscopy to detect multifocal papillary thyroid cancer. Metman MJH, Jonker PKC, Sondorp LHJ, van Hemel BM, Sywak MS, Gill AJ, Jansen L, van Diest PJ, van Ginhoven TM, Löwik CWGM, Nguyen AH, Robinson DJ, van Dam GM, Links TP, Coppes RP, Fehrmann