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Formation of toxic oligomers of polyQ-expanded Huntingtin by prion-mediated cross-seeding. Gropp MHM, Klaips CL, Hartl FU. Mol Cell. 2022 Oct 13:S1097-2765(22)00952-2. doi: 10.1016/j.molcel.2022.09.031. Online ahead of print.PMID: 36272412

The Giepmans groep heeft de Open Research Award toegekend gekregen voor de nPOD EM dataset (gepubliceerd op IDR). Lees meer   De award uitreiking  is op 17 November, 2022 (men kan het ook  online bijwonen).        

Patient-derived parathyroid organoids as a tracer and drug-screening application model Milou E. Noltes , Luc H.J. Sondorp, Laura Kracht, Adrienne H. Brouwers, Robert P. Coppes, Schelto Kruijff Stem cell reports, October 27, 2022

Getting on the right track: Interactions between viruses and the cytoskeletal motor proteins Rio Berge C, Cong Y, Reggiori F Traffic, in press.  

Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology Misrielal C, Alsema AM, Wijering MHC, Miedema A, Mauthe M, Reggiori F, Eggen BJL Brain Behav Immun Health, in press.

Digest it all: The lysosomal turnover of cytoplasmic aggregates Mauthe M, Kampinga HH, Hipp MS, Reggiori F Trends Biochem Sci, in press.

ER-phagy requires the assembly of actin at the contact sites between the cortical ER and endocytic pits Liu D, Mari M, Li X, Reggiori F, Ferro-Novick S, Novick P Proc Natl Acad Sci USA, 119, e2117554119.

mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation SCYL1 Kaeser-Pebernard S, Vionnet C, Mari M, Siva Sankar D, Hu Z, Roubaty C, Martinez E, Zhou H, Spuck-Calvar M, Petri-Fink A, Rainer G, Steinberg F, Reggiori F, Dengjel J Nat Comm, 13, 4685. 

The lipid flippase Drs2 regulates anterograde transport of Atg9 during autophagy (2022) Kriegenburg F, Huiting W, van Buuren-Broek F, Zwilling E, Hardenberg R, Mari M, Kraft C, Reggiori F Autophagy Rep, 1, 345–367.

The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis. F. Elsiena Kuiper, Paola Gallardo, Tessa Bergsma, Muriel Mari, Maiara Kolbe Musskopf, Jeroen Kuipers, Ben N. G. Giepmans, Anton Steen, Harm H. Kampinga, Liesbeth M. Veenhoff, Steven Berg