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The Holtman Group and the Netherlands Brain Bank were Awarded a Chan Zuckerberg Initiative Grant for an AI-Driven Research project. We are excited to announce that the Holtman lab, in collaboration with the Netherlands Brain Bank, has been awarded €300,000 in funding from the Chan Zuckerberg

Zebrafish and Japan: My journey to the 18th IZFC Conference | FEBS Network EARLY-CAREER SCIENTIST Attending an international conference as a PhD student, presenting new research, and meeting experts and potential collaborators, is a highlight of most doctoral studies. Here we learn how chance a

Published by the Hipp lab in collaboration with researchers involved at both the UMCG and the University of Oldenburg. Describing a technique that allows for visualization of multimerization of the transmembrane protein PRG5 at specific subcellular locations. Visualizing multimerization of plast

Future of Team-based Basic and Translational Science in Radiation Oncology. Coppes RP, van Dijk LV. Semin Radiat Oncol. 2024 Oct;34(4):370-378. doi: 10.1016/j.semradonc.2024.07.007. PMID: 39271272Review.

Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair. Korsten G, Osinga M, Pelle RA, Serweta AK, Hoogenberg B, Kampinga HH, Kapitein LC. J Cell Biol. 2024 Nov 4;223(11):e202307142. doi: 10.1083/jcb.202307142.

Sparing of the heart facilitates recovery from cardiopulmonary side effects after thoracic irradiation. Wiedemann J, Paruchuru SK, den Boef LE, Brouwer U, Silljé HHW, Schouten EM, Dickinson MG, van Goethem MJ, Coppes RP, van Luijk P. Int J Radiat Oncol Biol Phys. 2024 Aug 14:S0360-3016(24)0317

The PhD student Maiara Kolbe Musskopf participated in the “Science in Shorts” competition organized by Nature portfolio. She had to explain her research in a creative way under 1 minute and her video was selected to be in the YouTube library of Nature portfolio.”

DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity. Ryder BD, Ustyantseva E, Boyer DR, Mendoza-Oliva A, Kuska MI, Wydorski PM, Macierzyńska P, Morgan N, Sawaya MR, Diamond MI, Kampinga HH, Joachimiak LA. Structure. 2024 Jun 6;32(6):662-678.e8

Children’s brain cancer research gets £5m boost to cut treatment side effects. Read more

Interplay of Proteostasis Capacity and Protein Aggregation: Implications for Cellular Function and Disease Mark S. Hipp & F. Ulrich Hartl Journal Molecular Biology, May 2024, 168615.