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A molecular mechanism underlying genotype‐specific intrahepatic cholestasis resulting from MYO5B mutations Arend W. Overeem;  Qinghong Li;  Yi‐ling Qiu;  Fernando Carton‐Garciá;  Changsen Leng;  Karin Klappe;  Just Dronkers;  Nai‐Hua Hsiao;  Jian‐She Wang;  Diego Arango;

Pseudomonas aeruginosa lectin LecB impairs keratinocyte fitness by abrogating growth factor signalling Alessia Landi, Muriel Mari, Svenja Kleiser, Tobias Wolf, Christine Gretzmeier, Isabel Wilhelm,Dimitra Kiritsi, Roland Thünauer, Roger Geiger, Alexander Nyström, Fulvio Reggiori, Julie Claud

Leonie ter Braak ging op Sterren Stage bij radiobioloog prof. Rob Coppes in het protonenterhapiecentrum in ‘t UMCG te Groningen om meer te weten te komen over de voordelen van protonentherapie. Bekijk het filmpje op you tube.  Meer info op deze website. In Sterren Stage maken bekende Nede

Radiation-induced cellular senescence in salivary glands Promotor: Rob P. Coppes Co-promotor: L. Barazzuol dutch summary

North Sea progressive myoclonus epilepsy is exacerbated by heat, a phenotype primarily associated with affected glia. Lambrechts RA, Polet SS, Hernandez-Pichardo A, van Ninhuys L, Gorter JA, Grzeschik NA, de Koning-Tijssen MAJ, de Koning TJ, Sibon OCM. Neuroscience. 2019 Nov 1. pii: S0306-4522(1

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation Changsen Leng, Arend W. Overeem,  Fernando Cartón-Garcia,  Qinghong Li,  Karin Klappe,  Jeroen Kuipers,  Yingying Cui, Inge S. Zuhorn, Diego Arango, Sven C. D. van IJzendoorn. Published: Novem

4′-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN. Jeong SY, Hogarth P, Placzek A, Gregory AM, Fox R, Zhen D, Hamada J, van der Zwaag M, Lambrechts R, Jin H, Nilsen A, Cobb J, Pham T, Gray N, Ralle M, Duffy M, Schwanemann L, Rai P, Freed A

Cell-autonomous and non-cell autonomous protection of DNAJB6 in Huntington’s disease Promotores: Harm H. Kampinga & Erik W.G.M. Boddeke Details defense   English and Dutch Short Summary Stellingen

CHILDHOOD-ONSET MOVEMENT DISORDERS: mechanistic and therapeutic insights from Drosophila melanogaster Promotores: Ody C.M. Sibon and M.A.J. de Koning-Tijssen Co-promotor: T.J. de Koning Details defense Lekenpraatje Dutch Summary Stellingen

Vac8 spatially confines autophagosome formation at the vacuole. Hollenstein DM, Gómez-Sánchez R, Ciftci A, Kriegenburg F, Mari M, Torggler R, Licheva M, Reggiori F, Kraft C. J Cell Sci. 2019 Oct 24. pii: jcs.235002.  Pdf