Roles/tasks: PhD student
Experience: Yang earned his B.S. of Pharmacy in Chinese Medicine in 2013 from Tianjin University of Traditional Chinese Medicine, China. In 2016, he received his M.S. in Pharmacology from Peking Union Medical College, China. He then joined Eggen group in 2016 pursuing his Ph.D. in Neuroscience.
Microglia heterogeneity in response to peripheral inflammation
The functionality of the central nervous system (CNS) can be strongly influenced by peripheral challenges such as infection and trauma. Peripheral inflammation or inflammation is a major medical problem in various CNS disorders. Microglia are the tissue macrophages of the CNS, specifically tailored to their functions in the CNS including maintenance of homeostasis. Microglia are versatile cells that adopt a range of phenotypes that depend on the type, amount, duration and frequency of the stimulus they are exposed to. In my project, I’m investigating microglia heterogeneity in response to peripheral inflammation on a transcriptomic and epigenetic level.
Funding: China Scholarship Council, NWO, and BCN
Research group: Eggen group
Group leader: Bart Eggen